Experimental evaluation of the effect of filtration of diesel exhaust by biologic exposure indicators
| Autor: | Ulf Ulfvarson, Monica Dahlqvist, Thomas Sandström, Björn Bergström, Ulla Ekholm, Lars Lagerstrand, Barbara Figler, Asbjørn Nilsen, Leif Bjermer, Torkel Trønnes, Odd G. Nilsen |
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| Rok vydání: | 1995 |
| Předmět: |
Male
Diesel exhaust Nitrogen Dioxide Pulmonary compliance medicine.disease_cause Diesel engine complex mixtures Catalysis law.invention Diesel fuel chemistry.chemical_compound law Formaldehyde medicine Animals Nitrogen dioxide Particle Size Lung Lung Compliance Filtration Air Pollutants business.industry Airway Resistance Public Health Environmental and Occupational Health Exhaust gas Equipment Design Pneumonia respiratory system Soot Carbon Pulmonary Alveoli Disease Models Animal chemistry Environmental chemistry Pulmonary Diffusing Capacity Rabbits business Pulmonary Ventilation human activities Gasoline |
| Zdroj: | American journal of industrial medicine. 27(1) |
| ISSN: | 0271-3586 |
| Popis: | The airway resistance, compliance of the respiratory system, transfer factor, and alveolar volume of 33 healthy rabbits were studied before and after exposure to diluted diesel exhaust generated in an experimental motor. Three diesel fuels and two particle traps were tested. Subsequent to the post-exposure lung function measurements, the animals were sacrificed and the lungs were processed for morphologic examination. The concentrations of particles, nitrogen dioxide, and formaldehyde were measured. The inflammatory airway changes were most pronounced in animals exposed to exhaust from standard fuel. Small changes were identified in animals exposed to exhaust filtered through the catalytic trap as well or exposed to unfiltered exhaust from fuels intended for densely built-up areas. Increase in compliance of the respiratory system was associated with the concentration of soot particles and formaldehyde. Compliance decreased significantly in animals exposed to exhaust from standard fuel filtered through the particle traps and increased almost significantly in animals exposed to unfiltered exhaust from the same fuel. |
| Databáze: | OpenAIRE |
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