Neurophysiology of Avian Sleep: Comparing Natural Sleep and Isoflurane Anesthesia
| Autor: | van der Meij, Jacqueline, Martinez-Gonzalez, Dolores, Beckers, Gabriël J. L., Rattenborg, Niels C., Leerstoel Bolhuis, Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF), Afd Psychologische functieleer |
|---|---|
| Přispěvatelé: | Leerstoel Bolhuis, Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF), Afd Psychologische functieleer |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Thalamus Local field potential Electroencephalography Non-rapid eye movement sleep lcsh:RC321-571 avian brain 03 medical and health sciences 0302 clinical medicine slow-waves propagation mental disorders Medicine lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Original Research isoflurane anesthesia medicine.diagnostic_test business.industry General Neuroscience musculoskeletal neural and ocular physiology visual hyperpallium Neurophysiology Sleep in non-human animals Burst suppression 030104 developmental biology Columba livia Isoflurane Anesthesia NREM sleep burst suppression business 030217 neurology & neurosurgery psychological phenomena and processes medicine.drug Neuroscience |
| Zdroj: | Frontiers in Neuroscience, Vol 13 (2019) Frontiers in Neuroscience Frontiers in Neuroscience, 13. Frontiers Media S.A. |
| ISSN: | 1662-453X |
| Popis: | Propagating slow-waves in electroencephalogram (EEG) or local field potential (LFP) recordings occur during non-rapid eye-movement (NREM) sleep in both mammals and birds. Moreover, in both, input from the thalamus is thought to contribute to the genesis of NREM sleep slow-waves. Interestingly, the general features of slow-waves are also found under isoflurane anesthesia. However, it is unclear to what extent these slow-waves reflect the same processes as those giving rise to NREM sleep slow-waves. Similar slow-wave spatio-temporal properties during NREM sleep and isoflurane anesthesia would suggest that both types of slow-waves are based on related processes. We used a 32-channel silicon probe connected to a transmitter to make intra-cortical recordings of the visual hyperpallium in naturally sleeping and isoflurane anesthetized pigeons (Columba livia) using a within-bird design. Under anesthesia, the amplitude of LFP slow-waves was higher when compared to NREM sleep. Spectral power density across all frequencies (1.5-100 Hz) was also elevated. In addition, slow-wave coherence between electrode sites was higher under anesthesia, indicating higher synchrony when compared to NREM sleep. Nonetheless, the spatial distribution of slow-waves under anesthesia was more comparable to NREM sleep than to wake or REM sleep. Similar to NREM sleep, slow-wave propagation under anesthesia mainly occurred in the thalamic input layers of the hyperpallium, regions which also showed the greatest slow-wave power during both recording conditions. This suggests that the thalamus could be involved in the genesis of slow-waves under both conditions. Taken together, although slow-waves under isoflurane anesthesia are stronger, they share spatio-temporal activity characteristics with slow-waves during NREM sleep. |
| Databáze: | OpenAIRE |
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