Colonic impaction in guineapigs fed a chemically defined diet: a case report
| Autor: | McDonald Ps, Typpo Jt, Cornwell Se, Kelley St, Link Je, Gibson Sv, Wagner Je |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Peritonitis
Fecal Impaction Distension Acclimatization Guinea pig Colonic Diseases Animal science Pregnancy Cricetinae Lactation medicine Animals Ascending colon Food science Food Formulated General Veterinary Impaction business.industry medicine.disease Animal Feed Diet medicine.anatomical_structure Female Animal Science and Zoology business |
| Zdroj: | Laboratory Animals. 21:112-117 |
| ISSN: | 1758-1117 0023-6772 |
| DOI: | 10.1177/002367728702100205 |
| Popis: | Pathogen-free female Hartley guineapigs were divided into four diet groups to determine optimal nitrogen requirements for growth, pregnancy and lactation. Three chemically defined test diets varying in total nitrogen were compared with commercial guineapig feed. Within 13 days, 24 of 78 animals from the three test diet groups died or required euthanasia. Affected guineapigs were depressed, lost weight and had distended abdomens. Distension, impaction and, in most cases, rupture of the spiral of the ascending colon and subsequent peritonitis were observed at necropsy. Husbandry changes which resulted in a decreased incidence of impactions included increased acclimatization time on commercial feed post-shipping, decreased animal density per cage and cessation of water medication with oxytetracycline. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|