Patient characteristics associated with improvement in glycemic control following addition of an oral antidiabetic drug to DPP-4 inhibitor monotherapy in Japanese patients with type 2 diabetes mellitus (JDDM 60)
| Autor: | Shinobu Motohashi, Katsuya Yamazaki, Shigeru Tokita, Koichi Kawai, Hiroshi Maegawa, Jun-ichi Eiki, Akira Wakana, Kristy Iglay, Azuma Kanatsuka, Ai Hayashi |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases business.industry Biguanide medicine.drug_class Endocrinology Diabetes and Metabolism nutritional and metabolic diseases Type 2 Diabetes Mellitus Retrospective cohort study medicine.disease Sulfonylurea Gastroenterology Internal medicine Sitagliptin Diabetes mellitus Internal Medicine medicine Original Article business Dipeptidyl peptidase-4 medicine.drug Glycemic |
| Zdroj: | Diabetol Int |
| Popis: | AIMS: The current study evaluated patient demographics and clinical characteristics that associated with HbA1c reduction following addition of one oral antidiabetic drug (OAD) to DPP4i monotherapy. METHODS: A retrospective study was conducted using CoDiC database. Adult T2DM patients treated with sitagliptin monotherapy for ≥ 6 months and adding one OAD were extracted. Association between patient characteristics at the time of add-on OAD and following HbA1c reduction was assessed. RESULTS: Of 444 included patients, mean age was 62 years and 33% were female. All add-on OAD classes demonstrated further HbA1c reduction (p |
| Databáze: | OpenAIRE |
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