Successful living donor liver transplantation for fulminant hepatic failure that manifested immediately after cesarean delivery
Autor: | Kazuhiro Sugihara, Toshiyuki Uchida, Suguru Kikuchi, Akira Mori, Shinji Uemoto, Naohiro Kanayama, Kazunao Suzuki, Yoshimasa Horikoshi, Hiroaki Itoh |
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Rok vydání: | 2012 |
Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Biomedical Engineering Biophysics Bioengineering Liver transplantation Hepatitis Biomaterials Fulminant hepatic failure Pregnancy medicine Living Donors Humans Pregnancy Complications Infectious Hepatic encephalopathy business.industry Cesarean Section Glasgow Coma Scale General Medicine Liver Failure Acute medicine.disease Surgery Liver Transplantation Hepatic Encephalopathy Gestation Plasmapheresis Female Liver function business |
Zdroj: | ASAIO journal (American Society for Artificial Internal Organs : 1992). 58(2) |
ISSN: | 1538-943X |
Popis: | A 31-year-old pregnant woman was diagnosed as having acute hepatitis of unknown etiology and conservatively treated. An emergency cesarean delivery was performed 5 days later at 33 weeks and 3 days of gestation because of a gradual deterioration in liver function. Two days after the cesarean delivery, she lost consciousness in the evening (Glasgow coma scale [GCS] = 9) because of hepatic encephalopathy and was diagnosed as having fulminant hepatic failure (FHF). Five days after the cesarean delivery, the patient (blood type B) underwent a successful left lobe with caudate lobe (S1+2+3+4) liver transplantation from her father (blood type AB), an ABO-incompatible donor. At 1 year follow-up, she and her baby are in good medical condition. The drastic deterioration in hepatic function, despite intensive plasmapheresis and continuous hemodiafiltration, during the early postpartum period suggested a possible causative association between the termination of pregnancy and progression of FHF from acute hepatitis of unknown etiology. |
Databáze: | OpenAIRE |
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