Combined CT angiography and SPECT myocardial perfusion imaging for the detection of functionally relevant coronary stenoses
| Autor: | Ting Li, Zhi Dong, Rong‑Fang Shi, Jian-ming Li, Li‑Ren Zhang |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Male
Coronary angiography Cancer Research medicine.medical_specialty medicine.medical_treatment Computed tomography Coronary Angiography Revascularization Biochemistry Coronary artery disease Myocardial perfusion imaging X ray computed Genetics medicine Humans Molecular Biology Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Coronary Stenosis Myocardial Perfusion Imaging Middle Aged medicine.disease Coronary Vessels Predictive value Oncology Angiography Molecular Medicine Female Radiology Tomography X-Ray Computed business |
| Zdroj: | Molecular Medicine Reports. 7:1391-1396 |
| ISSN: | 1791-3004 1791-2997 |
| DOI: | 10.3892/mmr.2013.1354 |
| Popis: | The present study aimed to discuss and evaluate the diagnostic performances and incremental clinical values of combined computed tomography coronary angiography (CTCA) and single photon myocardial perfusion imaging (MPI) for the detection of functionally relevant coronary stenoses (FRCS). In total, 54 patients underwent CTCA, MPI and coronary angiography (CAG) within 30 days. The diagnostic performances of CTCA and combined CTCA plus MPI for the detection of significant coronary stenoses (≥50%) were calculated on the patient‑ or vessel‑based levels and included the indices of sensitivity (SN), specificity (SP), positive predictive value (PPV), negative predictive value (NPV) and accuracy (AC). On the patient‑based level, the SP, PPV, NPV and AC of CTCA alone or combined with MPI in the detection of FRCS were 90.9 and 90.9, 71.9 and 96.9, 69.0 and 95.2, 92.0 and 93.9 and 79.6 and 94.4%, respectively. On the vessel‑based level, the SN, SP, PPV, NPV and AC of CTCA alone or combined with MPI in the detection of FRCS were 90.3 and 90.3, 87.6 and 98.9, 54.9 and 93.3, 98.2 and 98.4 and 88.0 and 97.7%, respectively. The PPV, SP and AC of combined CTCA and MPI in the detection of FRCS were significantly improved compared with CTCA alone (all values, P |
| Databáze: | OpenAIRE |
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