EFFECT OF MITRAL REGURGITATION ON CHRONIC HEART FAILURE COURSE AND STRUCTURE-FUNCTIONAL HEART STATE
| Autor: | B. Y. Bart, M. P. Mikhaylusova, B. N. Mamtsev, V. N. Larina |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
митральная регургитация lcsh:Diseases of the circulatory (Cardiovascular) system RM1-950 хроническая сердечная недостаточность Internal medicine medicine.artery medicine Diseases of the circulatory (Cardiovascular) system Pharmacology (medical) Decompensation cardiovascular diseases Mitral regurgitation Ejection fraction business.industry lcsh:RM1-950 Furosemide medicine.disease chronic heart failure medicine.anatomical_structure Blood pressure lcsh:Therapeutics. Pharmacology Ventricle lcsh:RC666-701 RC666-701 Heart failure Pulmonary artery Cardiology mitral regurgitation Therapeutics. Pharmacology Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Racionalʹnaâ Farmakoterapiâ v Kardiologii, Vol 5, Iss 5, Pp 7-16 (2016) |
| ISSN: | 2225-3653 1819-6446 |
| Popis: | Aim. To evaluate chronic heart failure (CHF) course, functional and structural heart changes in patients with functional mitral regurgitation (MR) of various degrees.Material and methods. A total of 104 outpatients (60-85 y. o.) with CHF of functional class II-IV by NYHA and functional MR of I-II degrees and MR of III-IV degrees were included into the study groups.Results: Patients in both groups were comparable in sex, age, CHF duration, body mass index, systolic and diastolic blood pressure, clinical state by the clinical state scale, quality of life, anxious and depressive status. The majority of patients with MR III had significant left ventricle (LV) systolic dysfunction (p=0,029), severe CHF course (p=0,034), received furosemide (p=0.004) and digoxin (p=0,004). They had significant increase in end-diastolic dimension (pConclusion. MR can be considered as one of sensitive predictors of LV geometry and function alteration in CHF patients and play an important role in symptoms development. |
| Databáze: | OpenAIRE |
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