Long-term response after electrochemotherapy in patients with relapsed or refractory cutaneous melanoma
Autor: | Stefano Mori, Gianluca Di Monta, Ugo Marone, Maria Luisa Di Cecilia, Corrado Caracò, Gerardo Botti, Lucia Benedetto, Paolo A. Ascierto, Ester Simeone, Massimiliano Di Marzo, Nicola Mozzillo |
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Jazyk: | angličtina |
Rok vydání: | 2014 |
Předmět: |
Medicine(all)
Electrochemotherapy medicine.medical_specialty business.industry Biochemistry Genetics and Molecular Biology(all) Antineoplastic drug Melanoma General Medicine Bleomycin medicine.disease General Biochemistry Genetics and Molecular Biology Surgery chemistry.chemical_compound Long term response chemistry Refractory Cutaneous melanoma Poster Presentation medicine In patient business |
Zdroj: | Journal of Translational Medicine |
ISSN: | 1479-5876 |
Popis: | Background Treatment of early and multiple cutaneous unresectable recurrences is a major therapeutic problem with around 80% of patients relapsing within 5 years [1]. For lesions refractory to elective treatments, electrochemotherapy (ECT) involving electroporation combined with antineoplastic drug treatment appears to be a new potential option [2]. This study was undertaken to analyze the shortand long-term responses of lesions treated with ECT with intravenous injection of bleomycin in melanoma patients with in-transit disease or distant cutaneous metastases. |
Databáze: | OpenAIRE |
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