Different histological subtypes of peripheral lung cancer based on emphysema distribution in patients with both airflow limitation and CT-determined emphysema
| Autor: | Beomsu Shin, Won-Jung Koh, Myung Jin Chung, Hye Yun Park, Hojoong Kim, Hyun Lee, Sumin Shin |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Cancer Research Pathology medicine.medical_specialty Vital capacity Lung Neoplasms Context (language use) Adenocarcinoma Pulmonary Disease Chronic Obstructive 03 medical and health sciences FEV1/FVC ratio 0302 clinical medicine Risk Factors DLCO Forced Expiratory Volume medicine Humans Lung cancer Lung Aged Retrospective Studies COPD business.industry Smoking Middle Aged respiratory system medicine.disease respiratory tract diseases Cross-Sectional Studies medicine.anatomical_structure Pulmonary Emphysema 030228 respiratory system Oncology 030220 oncology & carcinogenesis Carcinoma Squamous Cell Female Tomography X-Ray Computed business |
| Zdroj: | Lung Cancer. 104:106-110 |
| ISSN: | 0169-5002 |
| Popis: | The histological subtypes by peripheral tumor location remain uncharacterized in COPD patients with emphysema. We investigated histologic subtypes of peripheral lung cancers based on the context of heterogeneous emphysema distribution in patients with airflow limitation and CT-determined emphysema. A retrospective, cross-sectional study was conducted using data from 754 patients with airflow limitation and newly-diagnosed primary lung cancers from February 2013 to February 2015. Of these, 230 patients had emphysema, as determined by computed tomography software designed to quantify emphysema. Among the 230 patients, the most common subtype in central lesions (n=84) was squamous cell carcinoma (SCC) (n=64/84, 76%). Adenocarcinoma (ADC) was more frequently observed in peripheral lesions (n=146) than central lesions (58/146 [40%] vs. 4/84 [5%], p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect