Estimates of Cancer Mortality Attributable to Carcinogenic Infections in Italy

Autor: Josep Maria Ramon-Torrell, Luciana Albano, Pietro Ferrara, Lorenzo G. Mantovani, Sara Conti, Fernando Agüero, Cristina Masuet-Aumatell
Přispěvatelé: Ferrara, P, Conti, S, Aguero, F, Albano, L, Masuet-Aumatell, C, Ramon-Torrell, J, Mantovani, L
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
Health
Toxicology and Mutagenesis
Population
lcsh:Medicine
medicine.disease_cause
Article
Helicobacter Infections
Causes of cancer
03 medical and health sciences
0302 clinical medicine
Neoplasms
Environmental health
Epidemiology of cancer
medicine
Humans
030212 general & internal medicine
education
Carcinogenic infection
carcinogenic infections
Hepatitis B virus
education.field_of_study
Cancer prevention
Helicobacter pylori
cancer prevention
biology
business.industry
allergology
Papillomavirus Infections
lcsh:R
Public Health
Environmental and Occupational Health
Cancer
burden of cancer mortality
Hepatitis B
medicine.disease
biology.organism_classification
Hepatitis C
DNA Virus Infections
Italy
cancer etiology
030220 oncology & carcinogenesis
modifiable risk factors
Female
business
Modifiable risk factor
Cancer Etiology
cancer epidemiology
Zdroj: International Journal of Environmental Research and Public Health, Vol 17, Iss 8723, p 8723 (2020)
International Journal of Environmental Research and Public Health
Volume 17
Issue 23
Popis: Several infectious agents are ascertained causes of cancer, but the burden of cancer mortality attributable to carcinogenic infections in Italy is still unknown. To tackle this issue, we calculated the rate and regional distribution of cancer deaths due to infections sustained by seven pathogens ranked as group 1 carcinogenic agents in humans by the International Agency for Research on Cancer. Population attributable fractions related to these agents were applied to annual statistics of cancer deaths coded according to the 10th International Classification of Diseases. The estimated burden of cancer mortality attributable to carcinogenic infections in Italy during the period 2011&ndash
2015 was 8.7% of all cancer deaths registered yearly, on average. Approximately 60% of deaths occurred in men, and almost the whole burden was due to four infectious agents (Helicobacter pylori, hepatitis C virus, high-risk human papillomavirus, and hepatitis B virus). The analysis of regional distribution showed a higher number of infection-related cancer deaths in the northern regions, where the estimates reached 30 (Liguria) and 28 (Friuli Venezia Giulia) deaths per 100,000 inhabitants in 2015. Since one-twelfth of cancer deaths were attributable to these modifiable risk factors, the implementation of appropriate prevention and treatment interventions may help to reduce the impact of these infections on cancer mortality.
Databáze: OpenAIRE
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