Marine diet and tobacco exposure affects mercury concentrations in pregnant women (I) from Baja California Sur, Mexico
| Autor: | Ramón Gaxiola-Robles, Lía C. Méndez-Rodríguez, Alfredo Celis, Rebecca L. Bentzen, Tania Zenteno-Savín, J. Margaret Castellini, Vanessa Labrada-Martagón, Todd M. O'Hara |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Monomethyl mercury
Health Toxicology and Mutagenesis chemistry.chemical_element Biology Toxicology Article Nutrient Animal science Pregnancy lcsh:RA1190-1270 Tobacco otorhinolaryngologic diseases lcsh:Toxicology. Poisons 2. Zero hunger chemistry.chemical_classification integumentary system Ecology Tobacco smoke exposure Mercury Fish consumption 3. Good health Mercury (element) chemistry Tobacco exposure sense organs Piscivory Body mass index Polyunsaturated fatty acid Hair |
| Zdroj: | Toxicology Reports, Vol 1, Iss C, Pp 1123-1132 (2014) Toxicology Reports |
| ISSN: | 2214-7500 |
| Popis: | Highlights • [THg] was measured in hair segments of women, reflecting exposure during pregnancy. • [THg] was noted to be significantly different by hair segment (three per individual). • Median hair [THg] in pregnant women from Baja California Sur, Mexico was 1.52 μg g−1. • Many (72%) of the participants had hair [THg] above 1 μg g−1. • Results suggest associations between [THg] and fish intake, BMI and tobacco exposure. Seafood provides essential polyunsaturated fatty acids (PUFA) and other nutrients to pregnant women and their fetus(es) while a diet rich in finfish can be a major pathway of monomethyl mercury (MeHg+) exposure. We measured total mercury concentration ([THg]) in hair samples provided by 75 women in Baja California Sur (BCS) to assess its relationship with age, parity, tobacco smoke exposure, and diet based on survey methodologies. Generalized linear models (GLM) were used to explain the possible association of the different variables with [THg] in hair. Median [THg] in hair was 1.52 μg g−1, ranging from 0.12 to 24.19 μg g−1 and varied significantly by segment. Approximately 72% (54/75) of those evaluated exceed 1 μg g−1 [THg] and 8% (6/75) exceed 5 μg g−1 [THg] in hair. Although frequency of fish consumption contributed significantly to explaining hair [THg], fish consumption only explained 43% of [THg] in a GLM incorporating tobacco exposure and body mass index. This study establishes possible relationships among multiple potential sources of exposure and other factors related to [THg] in hair of women in the prenatal period. A more detailed examination of other sources of exposure and factors contributing to [THg] is warranted. |
| Databáze: | OpenAIRE |
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