First report of feline morbillivirus in mainland China
| Autor: | Haibin Xu, Jijing Zhao, Zixin Ren, Gang Lu, Shoujun Li, Jiajun Ou, Shaotang Ye |
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| Rok vydání: | 2019 |
| Předmět: |
Mainland China
Male medicine.medical_specialty China Biology Kidney Genetic analysis 03 medical and health sciences Medical microbiology Phylogenetics Virology medicine Prevalence Animals Renal Insufficiency Chronic Gene Phylogeny 030304 developmental biology 0303 health sciences Genetic diversity Phylogenetic tree 030306 microbiology General Medicine Morbillivirus Cats RNA Viral Female Morbillivirus Infections |
| Zdroj: | Archives of virology. 165(8) |
| ISSN: | 1432-8798 |
| Popis: | Feline morbillivirus (FeMV) is an emerging member of the family Paramyxoviridae that is suspected to be involved in chronic kidney disease (CKD). FeMV was first discovered in Hong Kong in 2012 and has subsequently been detected in many countries. However, the prevalence of FeMV in mainland China is still unclear. To clarify the present status and examine the genetic diversity of FeMV in mainland China, in this study, we collected cat urine samples in veterinary hospitals in Guangdong Province in 2017 and 2018. Using reverse transcription (RT)-PCR, we found that the urine of six out of 64 cats tested positive for FeMV RNA. Sequencing and genetic analysis of the FeMV L gene showed that FeMV in mainland China is genetically diverse, and phylogenetic analysis showed that the viruses segregated into two clusters. Two isolates, GD5 and GD6, grouped in a branch that was separate from the one containing other previously reported FeMV isolates. These results will contribute to a better understanding of the evolution of FeMV in China. |
| Databáze: | OpenAIRE |
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