Construction of an automatic score for the evaluation of speech disorders among patients treated for a cancer of the oral cavity or the oropharynx: The Carcinologic Speech Severity Index

Autor: Corinne Fredouille, Alain Ghio, Corine Astésano, Virginie Woisard, Michèle Puech, Julien Pinquier, Jérôme Farinas, Benoit Lepage, Mathieu Balaguer, Muriel Lalain
Přispěvatelé: CHU Toulouse [Toulouse], Laboratoire Informatique d'Avignon (LIA), Centre d'Enseignement et de Recherche en Informatique - CERI-Avignon Université (AU), Équipe Structuration, Analyse et MOdélisation de documents Vidéo et Audio (IRIT-SAMoVA), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Laboratoire Parole et Langage (LPL), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de NeuroPsychoLinguistique (LNPL), Université Toulouse - Jean Jaurès (UT2J), USMR Support Unit for Research Methodology, Department of Epidemiology, Toulouse University Hospital, Toulouse, France, INCa 2014 C2SI project (Grant No.INCa-SHS- 2014-135), ANR-18-CE45-0008,RUGBI,Recherche d'unités linguistiques pertinentes pour améliorer la mesure de l'intelligibilité de la parole altérée par des troubles de production pathologique(2018), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Avignon Université (AU)-Centre d'Enseignement et de Recherche en Informatique - CERI, Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Université de Toulouse (UT)-Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI), Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Service Epidémiologie clinique et santé publique [CHU Toulouse], Pôle Santé publique et médecine publique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
severity index
medicine.medical_specialty
Speech production
oropharyngeal cancer
speech disorders
Audiology
Intelligibility (communication)
Logistic regression
[INFO.INFO-CL]Computer Science [cs]/Computation and Language [cs.CL]
phonétique clinique
Correlation
03 medical and health sciences
0302 clinical medicine
Quality of life
[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing
[INFO.INFO-LG]Computer Science [cs]/Machine Learning [cs.LG]
medicine
otorhinolaryngologic diseases
Humans
[SHS.LANGUE]Humanities and Social Sciences/Linguistics
030223 otorhinolaryngology
intelligibility
Mouth
business.industry
Speech Intelligibility
Cancer
oral cancer
Speech processing
medicine.disease
Comprehension
Oropharyngeal Neoplasms
parole
Otorhinolaryngology
030220 oncology & carcinogenesis
Quality of Life
business
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Zdroj: Head and Neck
Head and Neck, Wiley, In press, ⟨10.1002/hed.26903⟩
Head & Neck
Head & Neck, In press, ⟨10.1002/hed.26903⟩
ISSN: 1043-3074
1097-0347
DOI: 10.1002/hed.26903⟩
Popis: International audience; Background: Speech disorders impact quality of life for patients treated with oral cavity and oropharynx cancers. However, there is a lack of uniform and applicable methods for measuring the impact on speech production after treatment in this tumor location. Objective: The objective of this work is to (1) model an automatic severity index of speech applicable in clinical practice, that is equivalent or superior to a severity score obtained by human listeners, via several acoustics parameters extracted (a) directly from speech signal and (b) resulting from speech processing and (2) derive an automatic speech intelligibility classification (i.e., mild, moderate, severe) to predict speech disability and handicap by combining the listener comprehension score with self-reported quality of life related to speech. Methods: Eighty-seven patients treated for cancer of the oral cavity or the oropharynx and 35 controls performed different tasks of speech production and completed questionnaires on speech-related quality of life. The audio recordings were then evaluated by human perception and automatic speech processing. Then, a score was developed through a classic logistic regression model allowing description of the severity of patients' speech disorders. Results: Among the group of parameters subject to extraction from automatic processing of the speech signal, six were retained, producing a correlation at 0.87 with the perceptual reference score, 0.77 with the comprehension score, and 0.5 with speech-related quality of life. The parameters that contributed the most are based on automatic speech recognition systems. These are mainly the automatic average normalized likelihood score on a text reading task and the score of cumulative rankings on pseudowords. The reduced automatic YC2SI is modeled in this way: YC2SIp = 11.48726 + (1.52926 × Xaveraged normalized likelihood reading) + (−1.94e-06 × Xscore of cumulative ranks pseudowords). Conclusion: Automatic processing of speech makes it possible to arrive at valid, reliable, and reproducible parameters able to serve as references in the framework of follow-up of patients treated for cancer of the oral cavity or the oropharynx.
Databáze: OpenAIRE
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