Adrenal venous sampling for primary hyperaldosteronism in patients with concurrent chronic kidney disease
| Autor: | Mark Burshteyn, Debbie L. Cohen, Douglas L. Fraker, Scott O. Trerotola |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Pathology Urology Contrast-induced nephropathy Renal function urologic and male genital diseases Sensitivity and Specificity Nephropathy chemistry.chemical_compound Primary aldosteronism Phlebotomy Adrenal Glands Hyperaldosteronism medicine Humans Radiology Nuclear Medicine and imaging Renal Insufficiency Chronic Retrospective Studies Creatinine business.industry Acute kidney injury Reproducibility of Results Acute Kidney Injury Middle Aged medicine.disease female genital diseases and pregnancy complications chemistry Female Cardiology and Cardiovascular Medicine business Kidney disease |
| Zdroj: | Journal of vascular and interventional radiology : JVIR. 24(5) |
| ISSN: | 1535-7732 |
| Popis: | Purpose To assess the risk of developing contrast-induced nephropathy (CIN) and to evaluate the technical success of adrenal venous sampling (AVS) in patients with chronic kidney disease (CKD). Materials and Methods AVS was performed in 25 patients with primary hyperaldosteronism and concurrent CKD to distinguish between unilateral and bilateral adrenal disease. One of the 25 patients underwent repeat AVS, for a total of 26 samplings. All patients received a hydration protocol before and after the procedure. Acute kidney injury (AKI) (increase in creatinine of 0.5 mg/dL or>25% above baseline) and diagnostic yield were determined. Results CKD was stage III in 20 patients (80%), stage IV in 4 patients (16%), and stage V in 1 patient (4%). Median contrast volume was 25 mL (range, 10–250 mL). Of 26 studies, 25 (96%) were diagnostic; the one nondiagnostic AVS was repeated with success. Despite their elevated risks, only 2 of 25 patients (8%) developed AKI, and neither patient required treatment. Conclusions AVS can be performed safely with a high degree of technical success and low risk of CIN in patients with primary hyperaldosteronism and concurrent advanced CKD. |
| Databáze: | OpenAIRE |
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