Resistencia insulínica y otras expresiones del síndrome metabólico en niños obesos chilenos
Autor: | Salesa Barja Y, Antonio Arteaga Ll, Ana M Acosta B, M Isabel Hodgson B. |
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Jazyk: | Spanish; Castilian |
Rok vydání: | 2003 |
Předmět: |
medicine.medical_specialty
business.industry Type 2 Diabetes Mellitus General Medicine Overweight medicine.disease Obesity Hyperinsulinemia Endocrinology Blood pressure Insulin resistance Hyperlipidemia Child nutrition disorders Internal medicine Hypertension medicine medicine.symptom business Hyperinsulinism Body mass index |
Zdroj: | Revista médica de Chile, Volume: 131, Issue: 3, Pages: 259-268, Published: MAR 2003 Revista médica de Chile v.131 n.3 2003 SciELO Chile CONICYT Chile instacron:CONICYT |
Popis: | Background: Infantile obesity is a probable risk factor for the early appearance of chronic illnesses like Type 2 Diabetes Mellitus, Dislipidemia and Hypertension. Insulin Resistance (IR) appears as the common etiological mechanism. Aim: To describe metabolic complications associated to obesity in a group of Chilean children and to correlate them with IR, estimated through the homeostasis model assessment index (HOMA). Subjects and methods: We studied 88 children, 12±2.4 years old. Fifty two had severe obesity, 19 were overweight, and 17 had a normal weight (body mass index z score (BMIz): 4.7±1.6, 1.7±0.5 and 0.2±0.6 respectively, p 20 uU/ml) and 79% had IR (HOMA >3.8). These children also had a higher prevalence of acantosis nigricans than the overweight and normal counterparts (63, 10.5 and 0% respectively, p |
Databáze: | OpenAIRE |
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