Resistencia insulínica y otras expresiones del síndrome metabólico en niños obesos chilenos

Autor: Salesa Barja Y, Antonio Arteaga Ll, Ana M Acosta B, M Isabel Hodgson B.
Jazyk: Spanish; Castilian
Rok vydání: 2003
Předmět:
Zdroj: Revista médica de Chile, Volume: 131, Issue: 3, Pages: 259-268, Published: MAR 2003
Revista médica de Chile v.131 n.3 2003
SciELO Chile
CONICYT Chile
instacron:CONICYT
Popis: Background: Infantile obesity is a probable risk factor for the early appearance of chronic illnesses like Type 2 Diabetes Mellitus, Dislipidemia and Hypertension. Insulin Resistance (IR) appears as the common etiological mechanism. Aim: To describe metabolic complications associated to obesity in a group of Chilean children and to correlate them with IR, estimated through the homeostasis model assessment index (HOMA). Subjects and methods: We studied 88 children, 12±2.4 years old. Fifty two had severe obesity, 19 were overweight, and 17 had a normal weight (body mass index z score (BMIz): 4.7±1.6, 1.7±0.5 and 0.2±0.6 respectively, p 20 uU/ml) and 79% had IR (HOMA >3.8). These children also had a higher prevalence of acantosis nigricans than the overweight and normal counterparts (63, 10.5 and 0% respectively, p
Databáze: OpenAIRE