Serum creatine phosphokinase levels as an indicator of muscle injury following lumbar disc surgery: Comparison of fully endoscopic discectomy and microdiscectomy
| Autor: | Müge Dolgun, Altay Sencer, Yavuz Aras, Burcu Göker, Pulat Akin Sabanci, Ali Guven Yorukoglu, Mehmet Osman Akçakaya, Achmet Ali, Muhittin Emre Altunrende, Fahir Sencan, Aydin Aydoseli |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Microsurgery medicine.medical_specialty Visual analogue scale medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine Outcome Assessment Health Care medicine Back pain Humans 030212 general & internal medicine Diskectomy Creatine Kinase medicine.diagnostic_test biology business.industry Endoscopy General Medicine Middle Aged Surgery Oswestry Disability Index Back Pain Anesthesia biology.protein Female Creatine kinase Neurology (clinical) medicine.symptom business Body mass index 030217 neurology & neurosurgery |
| Zdroj: | Clinical Neurology and Neurosurgery. 145:74-78 |
| ISSN: | 0303-8467 |
| DOI: | 10.1016/j.clineuro.2016.04.004 |
| Popis: | The aim of this study is to make a comparison between fully endoscopic lumbar discectomy (FELD) and conventional microdiscectomy (MD) by using pre- and postoperative serum creatine phosphokinase (CPK) levels in correlation with postoperative low-back pain.Fortyfive consecutive patients who underwent surgery for lumbar disc herniation were allocated into three groups with 15 patients on each: (1) FELD with interlaminar approach (IL), (2) FELD with transforaminal approach (TF), (3) Conventional MD. Serum CPK levels pre- and 1, 6, 12 and 24h postoperatively, patients' body mass index (BMI), operation duration and hospital stays were recorded. The low-back pain pre- and postoperatively was assessed with the use of the 100mm visual analog scale (VAS) and the "Oswestry Disability Index" (ODI).There were 16 female (35.5%) and 29 male (64.5%) patients with a mean age of 44.1 years. CPK levels at 6th, 12th and 24th hours postoperatively were found significantly lower in TF and IL groups compared to MD group (p0.004). Mean operation duration was significantly shorter in MD group (p: 0.014). There was a significant decrease in both the VAS and ODI scores after the surgery in all patient groups (p0.001). Postoperative VAS scores were found significantly higher in MD group (p: 0.04).Minimal invasive nature of FELD procedures compared to the MD was substantiated by serum CPK levels in this study. To draw definitive conclusions regarding pain relief, larger patient samples should be evaluated, although postoperative VAS scores were found in favor of FELD. |
| Databáze: | OpenAIRE |
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