In vitro activity of cefodizime (HR-221)
| Autor: | Michael A. Shulman, Vincent I. Ahonkhai, C E Cherubin |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Cefotaxime
Aerobic bacteria medicine.drug_class Antibiotics Microbial Sensitivity Tests medicine.disease_cause Microbiology Cefodizime Enterobacteriaceae Staphylococcus epidermidis Streptococcus pneumoniae medicine Humans Pharmacology (medical) Pharmacology biology Bacteria Correction Drug Resistance Microbial Bacterial Infections biology.organism_classification Anti-Bacterial Agents Infectious Diseases Staphylococcus aureus Serratia marcescens medicine.drug Research Article |
| Zdroj: | Antimicrobial agents and chemotherapy. 22(4) |
| ISSN: | 0066-4804 |
| Popis: | The in vitro activity of cefodizime (HR-221), a new cephalosporin antibiotic, was compared with the activities of selected antimicrobial agents against a broad spectrum of aerobic bacteria. Cefodizime concentrations of 2 micrograms/ml inhibited about 90% of Enterobacteriaceae studied. Serratia marcescens required 8 micrograms/ml to inhibit 90% of strains. Among gram-positive cocci, 50% of strains were inhibited by 2 micrograms/ml of cefodizime (including methicillin-resistant Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus faecalis, and penicillin-resistant Streptococcus pneumoniae). Pseudomonas aeruginosa was less susceptible to cefodizime. Cefotaxime, an antibiotic closely related to cefodizime structurally, was about fourfold more active. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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