Lithogenic factors in postmenopausal women with osteoporotic fracture
| Autor: | Ochoa-Hortal Rull Ma, Arrabal-Martín M, Arrabal-Polo Ma, Cano-García Mc |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Endocrinology Diabetes and Metabolism Osteoporosis Hypercalciuria Urology Urine Phosphorus metabolism 03 medical and health sciences 0302 clinical medicine Endocrinology Urolithiasis Internal medicine Internal Medicine medicine Humans Citrates Aged Aged 80 and over Oxalates business.industry Middle Aged medicine.disease Hyperuricosuria Urinary calcium Postmenopause 030104 developmental biology Cross-Sectional Studies 030220 oncology & carcinogenesis Female business Body mass index Hypocitraturia Osteoporotic Fractures |
| Zdroj: | Minerva endocrinologica. 42(1) |
| ISSN: | 1827-1634 |
| Popis: | BACKGROUND The aim of this study was to show the presence of phosphorus and calcium metabolism disorders and the presence of urine lithogenic factors in women with osteoporotic fracture without previous urinary lithiasis. METHODS We conducted a cross-sectional study including 55 women with osteoporotic fracture surgically treated in the Trauma Department. We included women with osteoporotic fracture demonstrated by the fracture area, fracture mechanism and the presence of osteoporosis by bone densitometry. We analyzed phospho-calcium metabolism as well as the calciuria, oxaluria, citraturia and uricosuria levels with fasting and 24-hour urine study. The presence of abnormal calcium and phosphorus metabolism was compared between women with hypercalciuria and normocalciuria. RESULTS The 55 women had a mean age of 70.1±13.8 years and a mean body mass index of 27.9±3.8 kg/m2. Forty-percent of the patients showed hypercalciuria, 36.4% hyperoxaluria, 36.4% hypocitraturia, and 5.3% hyperuricosuria. When comparing patients with hypercalciuria and normocalciuria, the only statistically significant difference was fasting urinary calcium/creatinine levels (0.16 versus 0.08, respectively; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|