Vitamin A deficiency and caries susceptibility of rat molars
| Autor: | Suzanne S. Harris, Juan M. Navia |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Vitamin
Molar Dental Caries Susceptibility Tooth eruption Dentistry Physiology Dental Caries Salivary Glands chemistry.chemical_compound stomatognathic system medicine Animals Weaning General Dentistry biology Vitamin A Deficiency business.industry Body Weight Cell Biology General Medicine Buccal administration biology.organism_classification medicine.disease Streptococcus mutans Animals Suckling Rats Vitamin A deficiency stomatognathic diseases Otorhinolaryngology chemistry Female business |
| Zdroj: | Archives of Oral Biology. 25:415-421 |
| ISSN: | 0003-9969 |
| DOI: | 10.1016/0003-9969(80)90008-4 |
| Popis: | Exact timing of vitamin A deficiency to coincide with critical periods of tooth development is essential for evaluating the pre-eruptive ettect on caries or this nutritional deficiency. Rat dams were made vitamin A deficient (A − ) at parturition. Pups born and nursed by A − dams had virtually no vitamin A in their livers at weaning. Following weaning, both A − and vitamin A adequate (A + ) groups of pups were orally infected with Streptococcus mutans 6715 and fed a vitamin A adequate caries-promoting diet for 3 weeks. The A − pups had significantly higher caries scores than those in the A + group for buccal, sulcal and approximal deep dentinal areas. Salivary glands from A − pups were normal in histologic appearance at weaning as were their molars and incisors. Thus, experimental induction of vitamin A deficiency for a limited time before tooth eruption increased susceptibility of rat molars to caries but did not alter morphology of the salivary glands. Thus vitamin A deficiency alters rat tooth formation, particularly dentine, making it more susceptible to caries. |
| Databáze: | OpenAIRE |
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