Nutrition and Cardiovascular Diseases: Programming and Reprogramming
| Autor: | Ivis Levy Fernandes Martins, Emiliana Barbosa Marques, Thaís Alvim-Silva, Karyne Pollo de Souza, Samuel de Sousa Pedro, Christianne Bretas Vieira Scaramello |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Epigenomics
biology business.industry 020206 networking & telecommunications Context (language use) 02 engineering and technology Disease Bioinformatics Histone Functional food Cardiovascular Diseases Pregnancy Functional Food DNA methylation microRNA 0202 electrical engineering electronic engineering information engineering biology.protein Medicine Lactation 020201 artificial intelligence & image processing Epigenetics business Reprogramming Nutrition |
| Zdroj: | International Journal of Cardiovascular Sciences, Volume: 34, Issue: 2, Pages: 197-210, Published: 12 MAR 2021 International Journal of Cardiovascular Sciences v.34 n.2 2021 International Journal of Cardiovascular Sciences Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
| Popis: | The Developmental Origin of Health and Disease (DOHaD) is an area of science dedicated to studying the processes by which insults during critical periods of mammals development leading to physiological changes resultig in diseases throughout life. Studies point to a complex interaction between nutritional status in early life and cardiovascular system homeostasis in which maternal malnutrition during gestation and/or lactation, as well as early weaning, are associated with development of cardiovascular diseases in adulthood. In this context, epigenetic changes, such as DNA methylation, histone acetylation, and change in microRNA expression have been considered molecular bases of cellular plasticity, which can also be gender-dependent. Experimental studies have demonstrated that interventions encompassing the consumption of functional food/bioactive compounds, as well as energetic and nutrients adjustments on the diet, may attenuate or even prevent consequences associated with plasticity of development, improving cardiovascular health. This review aimed to gather and discuss the findings within this context, published over the last ten years. |
| Databáze: | OpenAIRE |
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