Delusional depression, family history, and DST response: A pilot study
| Autor: | Jan E. Lerbinger, Thomas C. Bond, Anthony J. Rothschild, Alan F. Schatzberg |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Male Proband Depressive Disorder medicine.medical_specialty Hydrocortisone Middle Aged Delusions Dexamethasone Alcoholism Dexamethasone suppression test medicine Humans Female Family history Psychiatry Psychology Cortisol level Biological Psychiatry Depression (differential diagnoses) Clinical psychology |
| Zdroj: | Biological Psychiatry. 21:1239-1246 |
| ISSN: | 0006-3223 |
| DOI: | 10.1016/0006-3223(86)90306-9 |
| Popis: | Results of the Dexamethasone Suppression Test (DST), performed on 65 patients with major unipolar depression, were classified both by suppression versus nonsuppression and by three ranges of postdexamethasone cortisol levels. Subgroups of patients were then compared for familial prevalence for depression and alcoholism and for delusional symptomatology. A strong association emerged among (1) high postdexamethasone cortisol levels, (2) a significantly increased familial prevalence for depression, and (3) the presence of delusions in probands. In this study, ranges of DST responses were superior to suppression versus nonsuppression criteria alone in defining this subgroup. |
| Databáze: | OpenAIRE |
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