Oral Colonization with Actinomyces Species in Infants by Two Years of Age
| Autor: | A. Kanervo, E. Könönen, P. Summanen, Hannele Jousimies-Somer, A. Takala, N. Sarkonen |
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| Rok vydání: | 2000 |
| Předmět: |
0301 basic medicine
Flora Saliva Colony Count Microbial Actinomyces sp Oral cavity Bacterial Adhesion Microbiology 03 medical and health sciences 0302 clinical medicine Actinomyces Humans Colonization Longitudinal Studies General Dentistry Genus Actinomyces biology Age Factors Mouth Mucosa Infant 030206 dentistry biology.organism_classification 030104 developmental biology Child Preschool Human mouth |
| Zdroj: | Journal of Dental Research. 79:864-867 |
| ISSN: | 1544-0591 0022-0345 |
| Popis: | In early childhood, the human mouth is already colonized by actinomycetes. Due to recent taxonomic changes within the genus Actinomyces, up-to-date data are warranted on the time and succession of different Actinomyces species in the oral cavity. By using a longitudinal study design and culture techniques, we examined the age-related occurrence of Actinomyces species in saliva from 39 healthy infants at 2, 6, 12, 18, and 24 months of age. Altogether 428 Actinomyces isolates were available for this study. Identification was based on biochemical tests and gas chromatographic demonstration of metabolic end-products, and when needed, cellular fatty acid profiles were determined. The frequency of the total actinomycetal flora increased from 31% to 97% within 2 years. A. odontolyticus was the most prominent Actinomyces colonizer at all five sampling occasions. A. naeslundii was the second most common Actinomyces sp. but was not detected before the age of 1 year. As a novel observation, we found A. graevenitzii in the oral cavity. The number of A. graevenitzii isolates indicates that this species is not just occasionally present in infants' mouths. We also found A. viscosus, A. gerencseriae, A. israelii, and A. georgiae. Based on the present results, we suggest that A. odontolyticus is the main primary Actinomyces species on oral mucosal surfaces in infants up to 2 years of age. |
| Databáze: | OpenAIRE |
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