HUMAN AMNIOTIC MEMBRANE TO CLOSE RECURRENT, HIGH MYOPIC MACULAR HOLES IN PATHOLOGIC MYOPIA WITH AXIAL LENGTH OF ≥30 mm

Autor: Stanislao Rizzo, Tomaso Caporossi, Lorenzo De Angelis, Francesco Barca, Bianca Pacini, Enrico Peiretti
Rok vydání: 2019
Předmět:
Male
0301 basic medicine
Pars plana
medicine.medical_specialty
Visual acuity
genetic structures
medicine.medical_treatment
Sulfur Hexafluoride
Visual Acuity
Vitrectomy
Endotamponade
03 medical and health sciences
0302 clinical medicine
Recurrence
Ophthalmology
human amniotic membrane
Pathologic myopia
medicine
Humans
recurrent high myopic macular hole
Amnion
Macular hole
Aged
Retrospective Studies
Aged
80 and over

business.industry
pathologic myopia
Settore MED/30 - MALATTIE APPARATO VISIVO
Internal limiting membrane
General Medicine
Axial length
Middle Aged
Retinal Perforations
medicine.disease
eye diseases
Axial Length
Eye

030104 developmental biology
medicine.anatomical_structure
Myopia
Degenerative

030221 ophthalmology & optometry
Female
sense organs
medicine.symptom
business
Tomography
Optical Coherence
Zdroj: Retina. 40:1946-1954
ISSN: 0275-004X
Popis: Purpose To assess the effectiveness of the human amniotic membrane plug for recurrent high myopic macular hole (MH) that already underwent pars plana vitrectomy with internal limiting membrane peeling and gas endotamponade. Methods Sixteen eyes of 16 patients with recurrent high myopic MH were enrolled. A 23-gauge pars plana vitrectomy was performed. Human amniotic membrane plugs were implanted under the neuroretina inside the MH. Twenty percent sulfur hexafluoride or air was used as endotamponades. The patients were instructed to maintain facedown position for 5 days after surgery. Results Optical coherence tomography examinations showed that the MHs closed in 15 of the 16 patients (93.75%) 2 weeks after one surgical intervention, and in 100% of patients after second intervention. Mean best-corrected visual acuity improved from 1 logarithm of the minimum angle of resolution (20/200) to 0.67 logarithm of the minimum angle of resolution (20/100) 6 months after surgery. Best-corrected visual acuity remained stable during the 12-month follow-up. One patient had human amniotic membrane plug dislocation after gas absorption that needed a second intervention with new AM plug implantation. No adverse events were reported during the 12-month follow-up. Conclusion The first case series of recurrent high myopic MH was reported, assessing the effectiveness of the human amniotic membrane plug to close recurrent MHs in pathologic myopia. All the cases were successful with encouraging best-corrected visual acuity recovery.
Databáze: OpenAIRE