Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke
| Autor: | William J. Powers, Allyson R. Zazulia, Michael N. Diringer, Tom O. Videen, Robert E. Adams, Colin P. Derdeyn, Edward M. Manno |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Ischemia Brain Edema Brain mapping Cerebral edema Bolus (medicine) Midline shift medicine.artery medicine Humans Mannitol Dominance Cerebral Infusions Intravenous Stroke Aged Aged 80 and over Brain Mapping business.industry Cerebral infarction Brain Infarction Middle Cerebral Artery Middle Aged medicine.disease Magnetic Resonance Imaging Anesthesia Middle cerebral artery Disease Progression Female Neurology (clinical) Atrophy Tomography X-Ray Computed Nuclear medicine business |
| Zdroj: | Neurology. 57:2120-2122 |
| ISSN: | 1526-632X 0028-3878 |
| DOI: | 10.1212/wnl.57.11.2120 |
| Popis: | Changes in brain tissue volume in six patients who had acute complete middle cerebral artery (MCA) infarctions and CT evidence of midline shift were measured using the brain boundary shift integral (BBSI) on sequential T1-weighted MR images acquired before and after a 1.5-g/kg bolus infusion of mannitol. At 50 to 55 minutes after the baseline scan, total brain volume decreased by 8.1 +/- 2.8 mL (0.6%, p < 0.005). Brain in the noninfarcted hemisphere shrank more (0.8 +/- 0.4%) than in the infarcted hemisphere (0.0 +/- 0.5%, p < 0.05). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|