In vivo evaluation of the effectiveness of biocellulose facial masks as active delivery systems to skin

Autor: Renato Redondi, Fabiola Cortinovis, Antonio Colpani, Mariella Bleve, Paola Perugini
Rok vydání: 2019
Předmět:
Adult
Dermatology
Wrinkle reduction
Administration
Cutaneous
in vivo study
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Cosmeceuticals
In vivo
Skin surface
Stratum corneum
Humans
Regeneration
Medicine
tolerability evaluation
Cellulose
Beneficial effects
Wrinkle
Skin
Drug Carriers
integumentary system
Gluconacetobacter xylinus
bacterial cellulose
business.industry
Polysaccharides
Bacterial
Original Contribution
Middle Aged
Settore ING-IND/35 - Ingegneria Economico-Gestionale
Elasticity
Healthy Volunteers
Skin Aging
cosmetic facial mask
efficacy evaluation
medicine.anatomical_structure
Face
030220 oncology & carcinogenesis
Skin color
Female
Basic Science Cosmetic Dermatology Articles
medicine.symptom
business
Skin roughness
Biomedical engineering
Zdroj: Journal of Cosmetic Dermatology
ISSN: 1473-2165
1473-2130
DOI: 10.1111/jocd.13051
Popis: Background In recent years, bacterial cellulose (BC), or biocellulose, a natural polymer synthesized by certain bacteria, has attracted great interest in dermatology and cosmetic applications. Several bioactive ingredients are currently loaded into BC masks. However, only a few studies have reported the effectiveness of such delivery systems. Aim The aim of this study was to evaluate the effect on skin parameters of three biocellulose masks formulated to have different cosmetic effects (anti‐aging, lifting, and cell renewal). In particular, skin moisturizing, skin color, skin viscoelastic properties, skin surface smoothness, wrinkle reduction, dermal homogeneity, and stratum corneum renewal were evaluated. Materials and methods The study involved 69 healthy Caucasian female volunteers between 25 and 64 years, who were divided into three different studies. Biocellulose facial masks were applied using the split‐face method three times a week for 4‐8 weeks depending on the study. Results The results obtained from this work highlight that biocellulose masks are very well tolerated. A significant decrease in skin roughness and wrinkle breadth, and an improvement in dermal homogeneity and firmness, was observed after 2 months of treatment with “anti‐aging” masks. A significant improvement in skin firmness and elasticity was observed after 1 month of treatment with “lifting” masks. Furthermore, a 1‐month treatment with “cell renewal” masks promoted the production of new skin cells through a mild exfoliating action. Conclusions This study highlights that biocellulose masks are effective delivery systems to successfully release into the skin several types of active compounds exerting many beneficial effects.
Databáze: OpenAIRE
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