Ebola (subtype Reston) virus among quarantined nonhuman primates recently imported from the Philippines to the United States
| Autor: | Thomas A. DeMarcus, Robert L. Peters, Pierre E. Rollin, Thomas W. Geisbert, Stephen Pearson, George Pucak, Peter B. Jahrling, Mark Cottingham, Diane M Simpson, C. J. Peters, Thomas G. Ksiazek, Katherine A. Hendricks, Sherif R. Zaki, Mike Kelley, David S. Bressler, Anthony Sanchez, R. Joel Williams, Sam G. Trappier, Patricia W. Greer |
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| Rok vydání: | 1999 |
| Předmět: |
Philippines
Filoviridae medicine.disease_cause Antibodies Viral Virus law.invention Disease Outbreaks Ebola Hemorrhagic Fever law Animals Laboratory Quarantine Medical Laboratory Personnel Immunology and Allergy Medicine Animals Humans Mononegavirales Antigens Viral Ebola virus biology business.industry Transmission (medicine) Reverse Transcriptase Polymerase Chain Reaction Monkey Diseases Outbreak Hemorrhagic Fever Ebola biology.organism_classification Ebolavirus Virology United States Macaca fascicularis Infectious Diseases business |
| Zdroj: | The Journal of infectious diseases. 179 |
| ISSN: | 0022-1899 |
| Popis: | In April 1996, laboratory testing of imported nonhuman primates (as mandated by quarantine regulations) identified 2 cynomolgus macaques (Macaca fascicularis) infected with Ebola (subtype Reston) virus in a US-registered quarantine facility. The animals were part of a shipment of 100 nonhuman primates recently imported from the Philippines. Two additional infected animals, who were thought to be in the incubation phase, were identified among the remaining 48 animals in the affected quarantine room. The other 50 macaques, who had been held in a separate isolation room, remained asymptomatic, and none of these animals seroconverted during an extended quarantine period. Due to the rigorous routine safety precautions, the facility personnel had no unprotected exposures and remained asymptomatic, and no one seroconverted. The mandatory quarantine and laboratory testing requirements, put in place after the original Reston outbreak in 1989-1990, were effective for detecting and containing Ebola virus infection in newly imported nonhuman primates and minimizing potential human transmission. |
| Databáze: | OpenAIRE |
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