Changes in Pulmonary Vascular Volumes after Induced Intravascular Aggregation of Blood Platelets

Autor: P. Aarseth, Jarle Vaage, I. Enge, J. Hognestad
Rok vydání: 1974
Předmět:
Zdroj: Acta Physiologica Scandinavica. 92:84-94
ISSN: 1365-201X
0001-6772
Popis: The volumes of intra- and extravascular fluid compartments in lungs have been studied in cats after intravascular aggregation of blood platelets induced by collagen infusions. Such infusions give marked pulmonary pressor responses. A biopsy-technique with removal of isolated lobes after isotopelabelling of the blood, indicated an increased vascular volume during the response to a collagen-infusion, while the extravascular water content remained unchanged. Angiographic observations revealed that the increased vascular volume is due to distension of large arteries, while the veins have a somewhat reduced dimension. These findings are interpreted as being caused by a precapillary vasoconstriction, no marked changes on capillary pressure, and with passive arterial dilatation upstreams to the constricted segments. Venous narrowing might be active or due to some passive recoil.
Databáze: OpenAIRE