Stereoselective synthesis of alpha-C-glucosyl serine and alanine via a cross-metathesis/cyclization strategy
| Autor: | Lawrence A Donahue, Jennifer M Potter, Michael D Orlando, Ernest G. Nolen, Adam J Kurish |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
chemistry.chemical_classification
Alanine Molecular Structure Chemistry Stereochemistry Alkene Organic Chemistry Stereoisomerism macromolecular substances Mercury Metathesis Biochemistry Catalysis Amino acid carbohydrates (lipids) Serine chemistry.chemical_compound Monomer Cyclization Stereoselectivity Physical and Theoretical Chemistry Glycoproteins |
| Zdroj: | Organic letters. 7(15) |
| ISSN: | 1523-7060 |
| Popis: | C-Glycosyl amino acids represent stable mimics of monomeric units within natural O-linked glycoproteins. Olefin cross-metathesis has been used to provide alkene precursors for a mercury(II)-mediated cyclization, yielding alpha-C-glucosyl serine and alanine. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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