Severe contiguous perianal Crohn's disease
| Autor: | Carlos Arthur de Figueiredo Athayde, Antonio Macedo D'Acri, Ricardo B. Lima, Helena R. Camasmie, Tricie K. Toledo, Omar Lupi, Carlos José Martins |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Case Report Dermatology Intertriginous Inflammatory bowel disease skin manifestations of internal diseases Lesion 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine Erythema nodosum Crohn's disease Gastrointestinal tract integumentary system business.industry Mucous membrane medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis CD Crohn's disease medicine.symptom business Pyoderma gangrenosum |
| Zdroj: | JAAD Case Reports |
| ISSN: | 2352-5126 |
| DOI: | 10.1016/j.jdcr.2016.01.010 |
| Popis: | Crohn's disease (CD) is an idiopathic inflammatory bowel disease that is characterized by noncaseating granulomas that occur in the gastrointestinal tract. This disease is chronic, incurable, and prone to relapse. CD is frequently associated with skin and mucous membrane lesions.1 The skin is among the most common sites for extraintestinal involvement in CD. Estimated incidence ranges from 22% to 44% and includes distant cutaneous (metastatic) CD, contiguous perianal CD, oral CD, reactive skin findings (including erythema nodosum and pyoderma gangrenosum), and nutritional skin changes.2 The site of involvement can influence lesion morphology. Contiguous cutaneous CD distinguishes from metastatic CD, as it extends directly from the gastrointestinal tract.3 Lesions that appear on the legs often present as intact inflammatory papules and plaques, whereas those involving intertriginous and genital skin usually ulcerate owing to the propensity for maceration in these sites.1 We describe a severe and extensive case of CD with perianal involvement contiguous to an anal CD lesion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|