Cardiac remodeling and dysfunction in childhood obesity: a cardiovascular magnetic resonance study

Autor: Brandon K. Fornwalt, Jennifer Rich, Gregory J. Wehner, Nivedita Umasankar, Frederick H. Epstein, H. Lester Kirchner, Linyuan Jing, Christopher M. Haggerty, Cassi M Binkley, Aurelia Radulescu, Sean M Hamlet, David K. Powell, Jonathan D. Suever, Christopher D. Nevius
Rok vydání: 2016
Předmět:
Male
Pediatric Obesity
Cardiac magnetic resonance
Heart disease
030204 cardiovascular system & hematology
Overweight
Ventricular Function
Left
030218 nuclear medicine & medical imaging
Ventricular Dysfunction
Left
0302 clinical medicine
Risk Factors
Prospective Studies
Age of Onset
Child
Adiposity
Observer Variation
Medicine(all)
Ejection fraction
Ventricular Remodeling
Radiological and Ultrasound Technology
Stroke volume
Biomechanical Phenomena
3. Good health
Cardiac mechanics
Cardiology
Female
Hypertrophy
Left Ventricular
medicine.symptom
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
Adolescent
Magnetic Resonance Imaging
Cine
Concentric hypertrophy
Childhood obesity
03 medical and health sciences
Predictive Value of Tests
Internal medicine
medicine
Humans
Radiology
Nuclear Medicine and imaging
Ventricular remodeling
Cardiac remodeling
Angiology
business.industry
Research
Reproducibility of Results
Stroke Volume
medicine.disease
Myocardial Contraction
Cross-Sectional Studies
Case-Control Studies
Stress
Mechanical
business
Zdroj: Journal of Cardiovascular Magnetic Resonance
ISSN: 1532-429X
DOI: 10.1186/s12968-016-0247-0
Popis: Background Obesity affects nearly one in five children and is associated with increased risk of premature death. Obesity-related heart disease contributes to premature death. We aimed to use cardiovascular magnetic resonance (CMR) to comprehensively characterize the changes in cardiac geometry and function in obese children. Methods and results Forty-one obese/overweight (age 12 ± 3 years, 56 % female) and 29 healthy weight children (age 14 ± 3 years, 41 % female) underwent CMR, including both standard cine imaging and displacement encoded imaging, for a complete assessment of left ventricular (LV) structure and function. After adjusting for age, LV mass index was 23 % greater (27 ± 4 g/m2.7 vs 22 ± 3 g/m2.7, p
Databáze: OpenAIRE
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