Effect of ketoconazole and miconazole on skeletal muscle mitochondrial calcium transport system

Autor:	A. M. Cheah, K.S. Cheah
Rok vydání:	1983
Předmět:	Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone medicine.medical_specialty Miconazole Swine Skeletal muscle mitochondria Antimycin A Biological Transport Active chemistry.chemical_element Mitochondrial calcium transport Pharmacology Calcium Piperazines Cellular and Molecular Neuroscience Oxygen Consumption Internal medicine Respiration medicine Animals Molecular Biology Chemistry Imidazoles Skeletal muscle Cell Biology Mitochondria Muscle Ketoconazole Endocrinology medicine.anatomical_structure Molecular Medicine Steady state (chemistry) medicine.drug
Zdroj:	Experientia. 39:290-293
ISSN:	1420-9071 0014-4754
Popis:	Both ketoconazole and miconazole inhibit the state 3 respiration induced by Ca2+, stimulate the state 4 respiration during succinate oxidation, inhibit the uptake of Ca2+ and also induce Ca2+ release in the aerobic steady state of skeletal muscle mitochondria. Miconazole is twice as effective as ketoconazole.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835ab8033bff61050aebc89e559477c0 https://doi.org/10.1007/bf01955310 Zobrazit plný text záznamu Full text from SpringerLink