Can a herd immunity strategy become a viable option against COVID-19? A model-based analysis on social acceptability and feasibility

Autor: Takara Sakai, Minoru Osawa, Takashi Akamatsu, Koki Satsukawa, Daijiro Mizutani, Takeshi Nagae
Jazyk: angličtina
Rok vydání: 2020
Předmět:
DOI: 10.1101/2020.05.19.20107524
Popis: This paper studies the social acceptability and feasibility of “herd immunity” strategies against coronavirus disease 2019 (COVID-19). To this end, we propose a control scheme that aims to develop herd immunity while satisfying the following two basic requirements for a viable policy option. The first requirement is social acceptability: the overall deaths should be minimized for social acceptance. The second is feasibility: the healthcare system should not be overwhelmed to avoid diverse adverse effects. Exploiting the fact that the severity of the disease increases considerably with age, the proposed control scheme protects high-risk individuals that mainly consist of the elderly. The protection of high-risk individuals reduces the average severity of the disease in the unprotected population, thereby substantially reducing mortality and avoiding the collapse of the healthcare system. Social acceptability (in terms of the resulting mortality) and feasibility (in terms of the healthcare system capacity) of the proposed herd immunity strategy are summarized into two respective, easily computable conditions by building on a simple susceptible–infected–recovered (SIR) model. For its parsimony, the proposed framework can provide a rule of thumb that applies to various populations for studying the viability of herd immunity strategies against COVID-19. For Japan, herd immunity may be developed by the considered control scheme ifand the severity rates of the disease are 1/10 times smaller than the previously reported value, although as high mortality as seasonal influenza is expected.
Databáze: OpenAIRE