Treatment of oral lichen planus by surgical excision and acellular dermal matrix grafting: Eleven case reports and review of literature
| Autor: | Qian Ding, Wen-Lin Xiao, Yao-Xiang Xu, Jin Yue, Zhen-Zhen Fu, Li-Qiang Chen |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Oral
medicine.medical_specialty integumentary system business.industry Grafting (decision trees) Surgical excision General Medicine medicine.disease Dermatology stomatognathic diseases 03 medical and health sciences 0302 clinical medicine stomatognathic system 030220 oncology & carcinogenesis Case report Medicine 030211 gastroenterology & hepatology Oral lichen planus Lichen planus skin and connective tissue diseases business Dermal matrix Acellular dermal matrix |
| Zdroj: | World Journal of Clinical Cases |
| ISSN: | 2307-8960 |
| Popis: | BACKGROUND Oral lichen planus (OLP) is a chronic inflammatory disorder, and it can affect normal oral function. The conventional treatments for OLP are not always effective, and relapse easily occurs. Therefore, treatment of OLP is difficult and challenging. In this study, we evaluated over a long period the clinical efficacy of surgical excision and acellular dermal matrix (ADM) grafting in patients with refractory OLP. CASE SUMMARY Eleven patients with refractory OLP underwent a standardized protocol of surgical excision and ADM grafting. The condition of the area of the grafted wound, the intraoperative maximum mouth opening, pain, and clinical healing were assessed at postoperative follow-up visits. All patients had a flat surgical area with similar mucosal tissue coverage and local scar formation. Patients had no irritation and pain in their mucous membranes when eating acidic and spicy food. All patients’ mouth openings returned to normal within 2-6 mo after surgery. During follow-up, none of the patients had recurrence of OLP after surgery. The longest follow-up was 11 yr and the shortest was 6 mo, and none of the patients relapsed during follow-up. CONCLUSION Surgical excision and ADM grafting could be an effective method to treat refractory OLP. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|