Paget's disease of the nipple in males: two case reports and literature review
| Autor: | Menglu Zhang, Xiangzhi Meng, Xin Wang, Jiaqi Liu, Zeyu Xing, Xiang Wang, Jie Wang |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty business.industry lcsh:R lcsh:Medicine Disease Modified Radical Mastectomy medicine.disease Dermatology Paget s disease Left breast Breast cancer lcsh:Biology (General) Male breast cancer otorhinolaryngologic diseases medicine Itching Left nipple medicine.symptom skin and connective tissue diseases business lcsh:QH301-705.5 |
| Zdroj: | Journal of Bio-X Research, Vol 1, Iss 2, Pp 89-94 (2018) |
| ISSN: | 2577-3585 2096-5672 |
| DOI: | 10.1097/jbr.0000000000000012 |
| Popis: | Male breast cancer accounts for less than 0.5%of all breast cancer, and Paget's disease of the breast in males is extremely rare. Here, we report 2 cases of Paget's disease of the nipple areola complex with invasive ductal carcinoma as typical examples of male PDB. Case 1 was a 64-year-old man with an altered appearance of the left nipple, itching and redness, without a palpable breast mass at first. Case 2 was a 55-year-old man with a palpable mass in the left breast and histologically confirmed Paget's disease of the nipple with invasive ductal carcinoma. Both patients underwent modified radical mastectomy but with different adjuvant therapies and remained well during follow-up with no recurrence. Furthermore, we reviewed all the sporadic cases of male PDB from the literature. This may help contribute to the development of diagnostic strategies and appropriate interventions for male Paget's disease of the breast. Key words: Paget's disease; male; clinical manifestations; treatment; prognosis |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|