Incidence of Malignancies Among Patients With Chronic Hepatitis B in US Health Care Organizations, 2006–2018

Autor: Philip R Spradling, Jian Xing, Yuna Zhong, Loralee B Rupp, Anne C Moorman, Mei Lu, Eyasu H Teshale, Mark A Schmidt, Yihe G Daida, Joseph A Boscarino, Stuart C Gordon
Rok vydání: 2022
Předmět:
Zdroj: The Journal of Infectious Diseases. 226:896-900
ISSN: 1537-6613
0022-1899
Popis: Hepatitis B virus (HBV) infection causes hepatocellular carcinoma but its association with other cancers is not well established. We compared age-adjusted incidence of primary cancers among 5773 HBV-infected persons with US cancer registries during 2006–2018. Compared with the US population, substantially higher incidence among HBV-infected persons was observed for hepatocellular carcinoma (standardized rate ratio [SRR], 30.79), gastric (SRR, 7.95), neuroendocrine (SRR, 5.88), cholangiocarcinoma (SRR, 4.62), and ovarian (SRR, 3.72) cancers, and non-Hodgkin lymphoma (SRR, 2.52). Clinicians should be aware of a heightened potential for certain nonhepatic malignancies among hepatitis B patients, as earlier diagnosis favors improved survival.
Databáze: OpenAIRE