Differences in proliferation, differentiation, and cytokine production by bone cells seeded on titanium–nitride and cobalt–chromium–molybdenum surfaces
| Autor: | Jenneke Klein-Nulend, Ruud P. van Hove, Peter A. Nolte, C.M. Semeins |
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| Přispěvatelé: | Oral Cell Biology, Orale Celbiologie (ORM, ACTA) |
| Rok vydání: | 2012 |
| Předmět: |
Chromium
inorganic chemicals Materials science medicine.medical_treatment Biomedical Engineering chemistry.chemical_element Cell Line Biomaterials Mice chemistry.chemical_compound Coated Materials Biocompatible Bone cell medicine Animals Cobalt chromium molybdenum Cell Proliferation Titanium Osteoblasts technology industry and agriculture Cell Differentiation Osteoblast Cobalt Prostheses and Implants Metabolism equipment and supplies Titanium nitride Cell biology medicine.anatomical_structure Cytokine chemistry Immunology Cytokines Implant |
| Zdroj: | Journal of Biomaterials Applications, 28(2), 278-287. SAGE Publications Ltd van Hove, R P, Nolte, P A, Semeins, C M & Klein-Nulend, J 2013, ' Differences in proliferation, differentiation, and cytokine production by bone cells seeded on titanium-nitride and cobalt-chromium-molybdenum surfaces ', Journal of Biomaterials Applications, vol. 28, no. 2, pp. 278-287 . https://doi.org/10.1177/0885328212440600 |
| ISSN: | 1530-8022 0885-3282 |
| DOI: | 10.1177/0885328212440600 |
| Popis: | Titanium–nitride coating is used to improve cobalt–chromium–molybdenum implant survival in total knee arthroplasty, but its effect on osteoconduction is unknown. Chromium and cobalt ions negatively affect the growth and metabolism of cultured osteoblasts while enhancing osteoclastogenic cytokine production. Therefore, it was hypothesized that a titanium–nitride surface would enhance osteoblast proliferation and/or differentiation and reduce osteoclastogenic cytokine production compared with a cobalt–chromium–molybdenum surface. MC3T3-E1 osteoblasts showed increased proliferation and decreased differentiation on titanium–nitride, while cytokine interleukin-6 production was higher on porous cobalt–chromium–molybdenum ( p |
| Databáze: | OpenAIRE |
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