Joint effect of alcohol drinking and tobacco smoking on all-cause mortality and premature death in China: A cohort study

Autor: Nanbo Zheng, Kangkang Yan, Chao Li, Xueyuan Bi, Zhang Hong-li
Rok vydání: 2021
Předmět:
Male
Longitudinal study
Epidemiology
Physiology
Social Sciences
030204 cardiovascular system & hematology
Overweight
Logistic regression
Habits
Endocrinology
Medical Conditions
0302 clinical medicine
Smoking Habits
Medicine and Health Sciences
Psychology
Medicine
Longitudinal Studies
030212 general & internal medicine
Aged
80 and over
Alcohol Consumption
Multidisciplinary
Cancer Risk Factors
Confounding
Middle Aged
Oncology
Physiological Parameters
Cohort
Female
medicine.symptom
Research Article
Cohort study
China
Alcohol Drinking
Endocrine Disorders
Science
03 medical and health sciences
Sex Factors
Tobacco Smoking
Diabetes Mellitus
Humans
Obesity
Aged
Nutrition
Behavior
business.industry
Body Weight
Biology and Life Sciences
Odds ratio
medicine.disease
Diet
Dyslipidemia
Medical Risk Factors
Metabolic Disorders
business
Demography
Zdroj: PLoS ONE, Vol 16, Iss 1, p e0245670 (2021)
PLoS ONE
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0245670
Popis: Background Tobacco smoking and alcohol drinking are associated with several diseases, and studies on the joint effects of smoking and drinking are rare. Objective This study investigates the joint effects of tobacco smoking and alcohol drinking on all-cause and premature mortality in a contemporary cohort. Methods The China Health and Retirement Longitudinal Study (CHARLS) is an ongoing nationally representative survey of subjects aged over 45 years in China that was performed every two years for a total of three waves from 2011 to 2015 in China. We used weighted logistic regression models to estimate the joint effects of tobacco smoking and alcohol drinking on all-cause and premature mortality. Results After adjusting for prespecified confounders, the odds ratios (ORs) of all-cause mortality were 1.51 (95% CI: 1.09–2.10) and 1.47 (95% CI: 1.03–2.08) in smokers and smokers/drinkers, respectively. Compared with nonsmokers/nondrinkers, the OR of smokers/drinkers for premature death was 3.14 (95% CI: 1.56–6.34). In the female subgroup, there was an approximately 5-fold (OR = 4.95; 95% CI: 2.00–12.27) odds of premature mortality for smokers/drinkers compared to nonsmokers/nondrinkers. Conclusion This study found a joint effect of tobacco smoking and alcohol drinking on all-cause and premature mortality among a contemporary and nationally representative cohort in China. Our results suggested that the joint effects were more pronounced in women, but further research is needed.
Databáze: OpenAIRE
Externí odkaz: