Adaptation in Bacillus cereus: From Stress to Disease
| Autor: | Michel Jobin, Catherine Duport, Philippe Schmitt |
|---|---|
| Přispěvatelé: | Duport, Catherine, Sécurité et Qualité des Produits d'Origine Végétale (SQPOV), Institut National de la Recherche Agronomique (INRA)-Avignon Université (AU), Avignon Université (AU)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Avignon Université (AU)-Institut National de la Recherche Agronomique (INRA) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Bacillus cereus redox homeostasis oxygen sensing acidic pH metabolism [SDV]Life Sciences [q-bio] 030106 microbiology lcsh:QR1-502 Review Disease structure cellulaire Microbiology lcsh:Microbiology cellular structures 03 medical and health sciences aliment ingéré entérotoxine Pathogen condition environnementale 2. Zero hunger Abiotic component oxygen deficiency Redox homeostasis biology anoxie fungi digestive oral and skin physiology bacillus cereus adaptation au stress biology.organism_classification Biochemistry Cereus ph acide Adaptation Diarrheal disease enterotoxin pathogen agent pathogène |
| Zdroj: | Frontiers in Microbiology (7), 18 p.. (2016) Frontiers in Microbiology Frontiers in Microbiology, Frontiers Media, 2016, 7, 18 p. ⟨10.3389/fmicb.2016.01550⟩ Frontiers in Microbiology, Vol 7 (2016) |
| ISSN: | 1664-302X |
| DOI: | 10.3389/fmicb.2016.01550⟩ |
| Popis: | Bacillus cereus is a food-borne pathogen that causes diarrheal disease in humans. After ingestion, B. cereus experiences in the human gastro-intestinal tract abiotic physical variables encountered in food, such as acidic pH in the stomach and changing oxygen conditions in the human intestine. B. cereus responds to environmental changing conditions (stress) by reversibly adjusting its physiology to maximize resource utilization while maintaining structural and genetic integrity by repairing and minimizing damage to cellular infrastructure. As reviewed in this article, B. cereus adapts to acidic pH and changing oxygen conditions through diverse regulatory mechanisms and then exploits its metabolic flexibility to grow and produce enterotoxins. We then focus on the intricate link between metabolism, redox homeostasis, and enterotoxins, which are recognized as important contributors of food-borne disease. |
| Databáze: | OpenAIRE |
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