Lenticulostriate vasculopathy in preterm infants: a new classification, clinical associations and neurodevelopmental outcome
| Autor: | Julide Sisman, Lina F. Chalak, Charles R. Rosenfeld, Marcia A. Pritchard, Roy J. Heyne, Devri L. Weakley, L. Steven Brown |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Gestational Age Infant Premature Diseases Lenticulostriate Vasculopathy 030218 nuclear medicine & medical imaging Congenital cmv infection 03 medical and health sciences 0302 clinical medicine 030225 pediatrics medicine Humans Prospective Studies Prospective cohort study Bronchopulmonary Dysplasia medicine.diagnostic_test business.industry Basal Ganglia Cerebrovascular Disease Case-control study Infant Newborn Obstetrics and Gynecology Gestational age Reproducibility of Results Echoencephalography Cranial ultrasound Logistic Models Case-Control Studies Pediatrics Perinatology and Child Health Cytomegalovirus Infections Gestation Female business Infant Premature |
| Zdroj: | Journal of perinatology : official journal of the California Perinatal Association. 38(10) |
| ISSN: | 1476-5543 |
| Popis: | To examine the inter-rater reliability for the diagnosis of LSV on cranial ultrasound (cUS), determine the risk factors associated with LSV and its progression, and examine neurodevelopmental outcome. Prospective case–control study of neonates ≤32wks of gestation assessed for LSV by serial cUS (n = 1351) between 2012 and 2014 and their neurodevelopment at 18–36mon-corrected age compared to controls. Agreement for LSV on cUS improved from Κappa 0.4–0.7 after establishing definitive criteria and guidelines. BPD was the only variable associated with the occurrence and the progression of LSV. Cytomegalovirus (CMV) infection occurred in one neonate (1.5%). Neurodevelopmental outcome of neonates with LSV did not differ from controls. Establishment of well-defined stages of LSV improves the reliability of the diagnosis and allows identification of neonates with progression of LSV. Although LSV was associated with BPD, it was not associated with congenital CMV infection. |
| Databáze: | OpenAIRE |
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