Folate-receptor 1 level in periodontal disease: a pilot study
| Autor: | Duygu Alkan, Berrak Guven, Çiğdem Coşkun Türer, Murat Can, Umut Balli |
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| Přispěvatelé: | BALLI, UMUT, Zonguldak Bülent Ecevit Üniversitesi |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Bleeding on probing Pilot Projects 02 engineering and technology Gastroenterology Pathogenesis 03 medical and health sciences Gingivitis Folic Acid 0302 clinical medicine Periodontal disease Internal medicine Folate-receptor 1 medicine Humans Folate Receptor 1 Periodontitis General Dentistry business.industry Gingival Crevicular Fluid 030206 dentistry 021001 nanoscience & nanotechnology medicine.disease Chronic periodontitis lcsh:RK1-715 lcsh:Dentistry Chronic Periodontitis Oral and maxillofacial surgery Female Folate receptor 1 Periodontal Index medicine.symptom 0210 nano-technology business Research Article |
| Zdroj: | BMC Oral Health BMC Oral Health, Vol 19, Iss 1, Pp 1-5 (2019) |
| Popis: | BackgroundThe purpose of this study was to investigate gingival crevicular fluid (GCF) and serum folate-receptor 1 (FOLR1) levels in subjects with different periodontal status.MethodsThe study consists of three groups: Healthy group (n = 15), gingivitis group (n = 15) and chronic periodontitis group (n = 15). Clinical periodontal parameters including probing pocket depth (PPD), clinical attachment level (CAL), gingival index (GI) and bleeding on probing (BOP) were assessed. GCF and serum samples were collected from each patient and were analyzed FOLR1 levels by enzyme-linked immunosorbent assay.ResultsThe values of FOLR1 in GCF were higher in gingivitis and periodontitis groups than among patient in control group (p p ConclusionsOur preliminary data suggest that FOLR1 is not useful in monitoring the periodontal disease. Further studies are necessary to clarify the role, regulation and function of folate and it’s receptors in the pathogenesis of periodontal disease. |
| Databáze: | OpenAIRE |
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