Long term outcome of unilateral pallidotomy: follow up of 15 patients for 3 years
| Autor: | Ali Samii, D. B. Calne, Michael Schulzer, I M Turnbull, S Yardley, E Mak, Pramod Kumar Pal, Asha Kishore |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Male medicine.medical_specialty Parkinson's disease Activities of daily living medicine.medical_treatment Globus Pallidus Central nervous system disease Activities of Daily Living Tremor medicine Humans Purdue Pegboard Test Pallidotomy Prospective cohort study Aged Dyskinesias business.industry Parkinson Disease Middle Aged medicine.disease nervous system diseases Psychiatry and Mental health Treatment Outcome Dyskinesia Papers Cohort Disease Progression Physical therapy Female Surgery Neurology (clinical) medicine.symptom business Follow-Up Studies |
| Zdroj: | Journal of Neurology, Neurosurgery & Psychiatry. 69:337-344 |
| ISSN: | 0022-3050 |
| DOI: | 10.1136/jnnp.69.3.337 |
| Popis: | OBJECTIVES—With the advent of new antiparkinsonian drug therapy and promising results from subthalamic and pallidal stimulation, this study evaluated the long term efficacy of unilateral pallidotomy, a technique which has gained popularity over the past decade for the management of advanced Parkinson's disease. METHODS—The 15 patients reported here are part of the original cohort of 24 patients who underwent posteroventral pallidotomy for motor fluctuations and disabling dyskinesias 3 years ago as part of a prospective study. Evaluation scales included the unified Parkinson's disease rating scale, the Goetz dyskinesia scale, and the Purdue pegboard test. RESULTS—When compared with the prepallidotomy scores, the reduction in the limb dyskinesias and off state tremor scores persisted on the side contralateral to pallidotomy at the end of 3 years (dyskinesias were reduced by 64% (p |
| Databáze: | OpenAIRE |
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