A close look at our cases with parathyroidectomy: 11 years of experience
| Autor: | Erdinc Erturk, Turkay Kirdak, Ozlem Saraydaroglu, Selin Narter, Mine Özşen |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Adenoma
Parathyroidectomy medicine.medical_specialty endocrine system diseases medicine.medical_treatment Endocrinology Diabetes and Metabolism medicine.disease_cause Endocrinology Internal Medicine Humans Medicine Parathyroid disease Thyroid neoplasm Retrospective Studies Parathyroid adenoma Hyperparathyroidism Hyperplasia business.industry Parathyroid neoplasm Carcinoma medicine.disease stomatognathic diseases Parathyroid Neoplasms Parathyroid carcinoma Radiology business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Minerva Endocrinology. 47 |
| ISSN: | 2724-6116 2724-6507 |
| Popis: | Background Hyperparathyroidism is caused by parathyroid adenoma, hyperplasia or carcinoma. Parathyroid adenomas are the most common cause of parathyroid disease (85-88%) while atypical parathyroid adenomas and carcinomas are the least frequently seen parathyroid neoplasms which cause diagnostic difficulty. This series aims to identifiy lesions of parathyroidectomy specimens in our center and draw attention to borderline cases in between parathyroid adenoma and carcinoma. Methods 638 parathyroidectomy materials diagnosed in our center between the years 2005 and 2016 were examined retrospectively and all were included in the study. Results In all the 638 parathyroidectomy cases evaluated, 427 were diagnosed with adenoma, 117 with hyperplasia, 54 with normal parathyroid tissue, 32 with parathyroid neoplasm with uncertain malignant potential, 7 with parathyroid carcinoma and 1 with normal thyroid tissue. Conclusions Parathyroid neoplasm with uncertain malignant potential defines cases with suspicious histopathological features of carcinoma but doesn't meet the criteria for parathyroid carcinoma. In our series, these cases are identified as atypical parathyroid adenoma. We present clinical and morphological features of our parathyroidectomy cases in an 11-year period and aim to raise concern about borderline cases in between adenoma and carcinoma. We think that such tumors, similar to the thyroid neoplasm classification, should be defined as parathyroid neoplasms with uncertain malignant potential and should be followed closely. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|