Creation of Certified Reference Material of Ascorbic Acid Composition
| Autor: | Mariya P. Krasheninina, Anna S. Sergeeva, V. B. Baranovskaya, Yuri A. Karpov, Olga S. Shokhina, Tatyana N. Tabatchikova |
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| Rok vydání: | 2020 |
| Předmět: |
Chromatography
Materials science Applied Mathematics 010401 analytical chemistry Isotope dilution Mass spectrometry Ascorbic acid 01 natural sciences High-performance liquid chromatography 0104 chemical sciences 010309 optics Certified reference materials Impurity Primary standard 0103 physical sciences Calibration Instrumentation |
| Zdroj: | Measurement Techniques. 63:314-324 |
| ISSN: | 1573-8906 0543-1972 |
| Popis: | The article presents the application of the “one hundred minus amount of impurities” approach in the development of a reference material of ascorbic acid composition using state primary and secondary measurement standards. The method of high-performance liquid chromatography (HPLC) with a detector on a diode array is used for the quantitative content of impurities of similar structure, with the highest content compared to other impurities. Traceability of certified values was provided using the calibration method of the State primary standard of units of mass (molar) fraction and mass (molar) concentration of organic components in liquid and solid substances and materials based on liquid and gas chromatography-mass spectrometry with isotope dilution and gravimetry GET 208-2019. The paper presents the use of the reference material of ascorbic acid composition to test the qualifications of laboratories, satisfactory results of the participants confirmed the applicability of the reference material for various measurement methods. |
| Databáze: | OpenAIRE |
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