The Beneficial Effect ofEquisetum giganteumL. againstCandidaBiofilm Formation: New Approaches to Denture Stomatitis

Autor: Nara Ligia Martins Almeida, Vanessa Soares Lara, Vinícius Carvalho Porto, Anne Lígia Dokkedal, Luiz Leonardo Saldanha, Rafaela Alves Da Silva Alavarce
Přispěvatelé: Universidade de São Paulo (USP), Universidade Estadual Paulista (Unesp)
Rok vydání: 2015
Předmět:
Zdroj: PubMed
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Evidence-Based Complementary and Alternative Medicine, Vol 2015 (2015)
Evidence-based Complementary and Alternative Medicine : eCAM
ISSN: 1741-4288
1741-427X
DOI: 10.1155/2015/939625
Popis: Made available in DSpace on 2015-12-07T15:34:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2015. Added 1 bitstream(s) on 2015-12-07T15:52:49Z : No. of bitstreams: 1 PMC4531177.pdf: 2455935 bytes, checksum: f43a0355a37eee2d18dbbb1909e90828 (MD5) Equisetum giganteum L. (E. giganteum), Equisetaceae, commonly called giant horsetail, is an endemic plant of Central and South America and is used in traditional medicine as diuretic and hemostatic in urinary disorders and in inflammatory conditions among other applications. The chemical composition of the extract EtOH 70% of E. giganteum has shown a clear presence of phenolic compounds derived from caffeic and ferulic acids and flavonoid heterosides derived from quercitin and kaempferol, in addition to styrylpyrones. E. giganteum, mainly at the highest concentrations, showed antimicrobial activity against the relevant microorganisms tested: Escherichia coli, Staphylococcus aureus, and Candida albicans. It also demonstrated antiadherent activity on C. albicans biofilms in an experimental model that is similar to dentures. Moreover, all concentrations tested showed anti-inflammatory activity. The extract did not show cytotoxicity in contact with human cells. These properties might qualify E. giganteum extract to be a promising alternative for the topic treatment and prevention of oral candidiasis and denture stomatitis. Department of Stomatology (Pathology), Bauru School of Dentistry, University of São Paulo (USP), Alameda Doutor Octávio Pinheiro Brisolla 9-75, 17012-901 Bauru, SP, Brazil. Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP, Brazil. Department of Prosthodontics, Bauru School of Dentistry, University of São Paulo (USP), Alameda Doutor Octávio Pinheiro Brisolla 9-75, 17012-901 Bauru, SP, Brazil. Department of Biological Sciences, Faculty of Sciences, São Paulo State University (UNESP), Bauru, SP, Brazil. Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP, Brazil. Department of Biological Sciences, Faculty of Sciences, São Paulo State University (UNESP), Bauru, SP, Brazil.
Databáze: OpenAIRE
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