Notable and Emerging Variants of SARS-CoV-2 Virus: A Quick Glance
| Autor: | Deepak N. Parchwani, Sagar Dholariya, Digishaben D. Patel, Anita Motiani, Ragini D. Singh, Amit Sonagra |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Infectivity
Transmission (medicine) SARS-CoV-2 SARS-CoV-2 nomenclature viruses Clinical Biochemistry Virulence virus diseases Context (language use) Review Article Biology medicine.disease_cause Virology Virus Notable variants Genomic surveillance Monoclonal medicine Transmission Viral load Coronavirus |
| Zdroj: | Indian Journal of Clinical Biochemistry |
| ISSN: | 0974-0422 0970-1915 |
| Popis: | Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiological agent of coronavirus disease-2019 (COVID-19), is a highly contagious pathogenic coronavirus to emerge and spread in human populations. Although substantial exertions have been laid to avert spread of COVID-19 by therapeutic and preventive countermeasures, but emergence of SARS-CoV-2 variants as a result of mutations make the infection more ominous. New viral confers a higher nasopharyngeal viral load, increased viral transmissibility, higher infectiousness, immune escape, increased resistance to monoclonal/polyclonal antibodies from convalescence sera/vaccine, and an enhanced virulence. Thus, it is pertinent to monitor evolving mutations and genetic diversity of SARS-CoV-2 as it is decisive for understanding the viral variants. In this review we provide an overview of colloquial nomenclature and the genetic characteristics of different SARS-CoV-2 variants in the context of mutational changes of the circulating strains, transmissibility potential, virulence and infectivity. |
| Databáze: | OpenAIRE |
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