Relation of atrial pressure and plasma level of atrial natriuretic factor in cardiac tamponade

Autor: Paul N. Casale, Robert M. Graham, Igor F. Palacios, Michael A. Fifer
Rok vydání: 1994
Předmět:
Zdroj: The American Journal of Cardiology. 73:610-613
ISSN: 0002-9149
DOI: 10.1016/0002-9149(94)90346-8
Popis: There has been a great deal of interest in the factors that stimulate secretion of atrial natriuretic factor (ANF) since its discovery in membrane-bound granules of atrial myocardial cells. 1,2 It is known that chronically elevated atrial pressures are associated with elevated plasma levels of ANF. 3–5 In addition, it has been shown that acute elevation of right and left atrial pressures produces a corresponding increase in ANF level. 6,7 In vitro work using isolated atria has demonstrated that stretching the atria by increasing tension results in an increased release of ANF. 8 To assess the effect of acute change in transmural atrial pressure on plasma level of ANF in humans, we measured ANF levels before and immediately after pericardiocentesis in 13 patients with pericardial effusion.
Databáze: OpenAIRE