Interference of Nontypeable Haemophilus Influenzae and Moraxella Catarrhalis by Streptococcus Oralis in Adenoid Organ Culture: A Possible Strategy for the Treatment of the Otitis-Prone Child
| Autor: | Michael Belmont, Diane Dryja, Joel M. Bernstein, Judy Wolf, Frank A. Scannapieco, Howard Faden |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
0301 basic medicine
medicine.disease_cause Adenoid Microbiology Haemophilus influenzae Moraxella catarrhalis 03 medical and health sciences Organ Culture Techniques 0302 clinical medicine Nasopharynx Antibiosis otorhinolaryngologic diseases Humans Medicine Child Moraxella biology business.industry Pasteurellaceae Streptococcus oralis 030206 dentistry General Medicine biology.organism_classification Otitis Media stomatognathic diseases 030104 developmental biology Otitis medicine.anatomical_structure Otorhinolaryngology Viridans streptococci Adenoids Immunology medicine.symptom business |
| Zdroj: | Annals of Otology, Rhinology & Laryngology. 111:696-700 |
| ISSN: | 1943-572X 0003-4894 |
| Popis: | The role of viridans group streptococci (Streptococcus oralis) in the prevention of colonization with nontypeable Haemophilus influenzae and Moraxella catarrhalis was investigated in an adenoid organ culture system. The adenoids from 100 patients who were undergoing adenoidectomy for either hypertrophy or recurrent otitis media were used. Streptococcus oralis Parker uniformly inhibited colonization with nontypeable H influenzae or M catarrhalis over a 24-hour period of incubation in adenoid organ culture. Streptococcus oralis Booth, a noninhibitory strain, did not significantly reduce colonization with nontypeable H influenzae and M catarrhalis. The results indicate that some strains of S oralis may inhibit colonization with potential pathogens in the nasopharynx. It is therefore possible that colonization with inhibitory strains of viridans streptococci may be used in the nasopharynx as a relatively safe and inexpensive approach to prevention of recurrent otitis media in some children. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|