Model for End-Stage Liver Disease, Model for Liver Transplantation Survival and Donor Risk Index as predictive models of survival after liver transplantation in 1,006 patients
| Autor: | Elisa Maria de Camargo Aranzana, Mauricio Alves Ribeiro, Luiz Arnaldo Szutan, Paulo Celso Bosco Massarollo, Adriana Zuolo Coppini, Fabio Gonçalves Ferreira |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Cirrhosis Adolescent Waiting Lists medicine.medical_treatment Liver transplantation Gastroenterology Risk Assessment Sensitivity and Specificity Severity of Illness Index End Stage Liver Disease Liver disease Young Adult Model for End-Stage Liver Disease Predictive Value of Tests Internal medicine Risk index Medicine Humans Mortality Survival analysis Aged Proportional Hazards Models Retrospective Studies lcsh:R5-920 Models Statistical business.industry Proportional hazards model Hazard ratio General Medicine Clinical Science Middle Aged medicine.disease Tissue Donors Surgery Epidemiological factors Survival Rate Multivariate Analysis Female business lcsh:Medicine (General) Brazil |
| Zdroj: | Clinics Clinics, Vol 70, Iss 6, Pp 413-418 (2015) Clinics, Volume: 70, Issue: 6, Pages: 413-418, Published: JUN 2015 Clinics; v. 70 n. 6 (2015); 413-418 Clinics; Vol. 70 Núm. 6 (2015); 413-418 Clinics; Vol. 70 No. 6 (2015); 413-418 Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 1980-5322 1807-5932 |
| Popis: | OBJECTIVES: Liver transplantation has not increased with the number of patients requiring this treatment, increasing deaths among those on the waiting list. Models predicting post-transplantation survival, including the Model for Liver Transplantation Survival and the Donor Risk Index, have been created. Our aim was to compare the performance of the Model for End-Stage Liver Disease, the Model for Liver Transplantation Survival and the Donor Risk Index as prognostic models for survival after liver transplantation. METHOD: We retrospectively analyzed the data from 1,270 patients who received a liver transplant from a deceased donor in the state of São Paulo, Brazil, between July 2006 and July 2009. All data obtained from the Health Department of the State of São Paulo at the 15 registered transplant centers were analyzed. Patients younger than 13 years of age or with acute liver failure were excluded. RESULTS: The majority of the recipients had Child-Pugh class B or C cirrhosis (63.5%). Among the 1,006 patients included, 274 (27%) died. Univariate survival analysis using a Cox proportional hazards model showed hazard ratios of 1.02 and 1.43 for the Model for End-Stage Liver Disease and the Model for Liver Transplantation Survival, respectively (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|