The analysis of mitochondrial data indicates the existence of population substructure in Karayaka sheep
| Autor: | Marcel Amills, Koray Kirikçi, Mehmet Akif Cam, Antonia Noce, Levent Mercan |
|---|---|
| Přispěvatelé: | CSIC - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Ministerio de Economía y Competitividad (España), Generalitat de Catalunya, Kırşehir Ahi Evran Üniversitesi, Ziraat Fakültesi, Zootekni Bölümü, Ondokuz Mayıs Üniversitesi |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Karayaka Population subdivision Population Zoology Biology Analysis of molecular variance Haplogroup Genetic diversity Fixation index 03 medical and health sciences Food Animals Turkish ovine breeds education Mitochondrial control region education.field_of_study 0402 animal and dairy science 04 agricultural and veterinary sciences biology.organism_classification 040201 dairy & animal science Breed 030104 developmental biology Genetic distance Animal Science and Zoology |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| Popis: | In the current study, we investigated the existence of population substructure in the Karayaka sheep breed from Turkey. A fragment of the mitochondrial D-loop region has been successfully sequenced in 69 Karayaka sheep sampled in the districts of Çarsamba, Bafra and Ladik. Though the B haplogroup was the most abundant in these three subpopulations, haplogroup frequencies and nucleotide diversities were remarkably different. The analysis of molecular variance (AMOVA) showed the existence of a significant (P-value = 0.019) between-subpopulations component representing 5.14% of the total variation. Moreover, phylogenetic analyses showed that the fixation index (FST) and the GammaST genetic distance between Karayaka subpopulations are similar to those observed between certain Turkish sheep breeds. We conclude that there is a significant population substructure in Karayaka sheep. Since breeds do not behave as single panmictic populations, this result could probably be extrapolated to other ovine breeds. Noteworthy, population substructure can have adverse effects on the maintenance of breed diversity and it is an important confounder effect in genome-wide-association studies. This research was partially funded by a grant (RZ2011-00015-C03-01) from the Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (Spain). We also acknowledge the support of the Spanish Ministry of Economy and Competitiveness for the Center of Excellence Severo Ochoa 22016-20192 (SEV-2015-0533) grant awarded to the Centre for Research in Agricultural Genomics.Thanks also to the CERCA Programme of the Generalitat de Catalunya. |
| Databáze: | OpenAIRE |
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