Validity of two point-of-care glucometers in the diagnosis of neonatal hypoglycemia
| Autor: | Thrathip Kolatat, Ratchada Kitsommart, K. Jeerapaet, P. Vutrapongwatana, L Inchgam, Sopapan Ngerncham, S. Piriyanimit, Pimol Wongsiridej |
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| Rok vydání: | 2012 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Pediatrics Point-of-Care Systems Point-of-care testing Hypoglycemia Infant Newborn Diseases Neonatal Screening Predictive Value of Tests Internal medicine Positive predicative value Pediatric surgery Humans Medicine Neonatology Prospective Studies Point of care Pregnancy Hematology business.industry Maternal and child health Neonatal hypoglycemia Infant Newborn Reproducibility of Results Thailand medicine.disease Test (assessment) Pulmonology Pediatrics Perinatology and Child Health business Blood Chemical Analysis |
| Zdroj: | Indian Pediatrics. 49:621-625 |
| ISSN: | 0974-7559 0019-6061 |
| Popis: | Background: Neonatal hypoglycemia can cause serious longterm neurodevelopmental outcome. A valid point-of-care glucometer is needed for diagnosis of neonatal hypoglycemia which is in a lower blood glucose range than diabetic patients. Aim: To estimate validity of two point-of-care glucometers for diagnosis of neonatal hypoglycemia and to determine the cut-off values for which standard laboratory confirmatory test are no longer needed. Methods: There were 180 blood specimens included. Nova StatStripTM and SureStepTM were operated at the bedside immediately after blood drawn. Laboratory tests were done within one hour. Results: On average, most of the blood glucose read-outs from Nova StatStripTM and SureStepTM were higher than laboratory plasma glucose throughout the glucose range with mean differences of 11.2±8.4 mg/dL and 13.7±6.8 mg/dL, respectively. Sensitivity, specificity, positive and negative predictive values were demonstrated. (Table 1) To obtain 100% negative predictive values, the cut-off levels were 63 mg/dL and 62 mg/dL for Nova StatStripTM and SureStepTM, respectively. Table Conclusions: None of the glucometers studied has sufficient validity to replace laboratory testing in diagnosing hypoglycemia. Confirmatory plasma glucose for diagnosis of hypoglycemia is needed when point-of-care glucometer readings are between 39 and 63 mg/dL for Nova StatStripTM and between 39 and 62 mg/dL for SureStepTM. |
| Databáze: | OpenAIRE |
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